I'm the areas I hunt one place might have a 50yd max shot where 200yds away it might be out to as far as you feel capable. By and far most of the shots I take on critters are in the range measured in feet as I go into the thick stuff after feral hogs with revolvers. I'm not really mad at the deer anymore, but the hogs, well they are top of my seek and destroy list.
That said, I do practice shooting out to 350yds on a pretty regular basis. When I do I usually start off form the bench them move on to field positions where I am utilizing my knees and elbows as rest. I also am a VERY firm believer in the Harris bi-pods and use them when I can.
I am very comfortable shooting deer or hogs out to 400yds, with the appropriate rifle, and in excellent conditions. IF things are even iffy I simply walk on down the road. With my revolvers and open sights I am good out to 50 with most and to 100 with others, but then again the situation and conditions will dictate the shot.
My furtherest deer was taken at a bit over 400yds with my 25-06 and a load which I have been shooting almost since I got it. The conditions were perfect, no wind, and sun from my back illuminating the target. The deer was observed for over half an hour and was simply standing and feeding on acorns under the edge of a big oak, in the middle of a pasture.
With my TC in 7x30 Waters I took a 287yd shot on a doe after nearly a two hour spot and stalk, which is clearly one of my most fond hunts to have been on. The range was lasered and she also was standing broadside feeding under some pin oaks. I knew the load and at the shot she simply jumped straight up and collapsed in a heap. The 140gr Nosler BT did an awesome job of taking out all vitals and the offside shoulder as it exited.
I personally do not have an issue with folks who put in the time and effort to learn their rifle/handgun and their loads. I do however feel that too much emphasis has been put on the so called "premium" bullets being able to preform miracles, and all one need to do is hit the animal from any direction and it is down. I have way more tolerance for someone shooting deer with a known load and rifle, than one who purchased the premium ammo and shoots any game animal from a less than good angle hoping that the bullet will drive through to the vitals like someone on a forum suggested it would. These same folks who usually tout the premium bullets and raking shots from ham to ear hole, are usually the same ones who are first to condemn someone for shooting beyond some magical range limit that they feel comfortable with, as being unethical.
Don't get me wrong, there is a place for premium type bullets, and I use them myself, but I do not rely on them to go from a-hole to appetite and do the job. I still put them through both shoulders and/or the vitals, or simply I do not shoot period. Like I said in the beginning, I'm not as mad at the deer family as I once was, but even so, now like then, I still wait until the shot needed can be taken, or it doesn't get taken at all.