I'm new to guns and home defense myself but after absorbing months of info online and from friends I chose a used Smith & Wesson 66-1 for my first gun for the reasons mentioned: relative simplicity of a revolver, potency of .357 for defense and ability to shoot milder .38s. Couple that with the legenday S&W name and an easier to maintain stainless steel version, it was the right choice for me. I did want an older Smith however because the newer ones have an onboard lock which in a few instances has failed... this is a big can of worms that I don't mean to open, I just wanted an older pre-lock model (plus, I like antiquity).
The S&W 686 seems to be universally loved and I don't think you can go wrong. If you can, do try out a few handguns beforehand whether at a range that rents or if you have acquainances with them
I enjoy range trips a lot; shooting is a lot of fun and actually quite relaxing. I hope you and your wife find enjoyment in it as well.
Good luck and be safe.
The S&W 686 seems to be universally loved and I don't think you can go wrong. If you can, do try out a few handguns beforehand whether at a range that rents or if you have acquainances with them
I enjoy range trips a lot; shooting is a lot of fun and actually quite relaxing. I hope you and your wife find enjoyment in it as well.
Good luck and be safe.