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Coltdriver--Nothing quite like gazing @ yr own creations, now, is there?
I don't load 125's, so can't help you there.
As to number of loadings for .357 magnum brass: With my target loads, I was once anal about keeping each lot of brass separate and keeping track of the number of times it had been loaded. While good with rifle rounds, I no longer do that for pistol cases. Anyhow, during that time I'd gotten into the teens for number of reloadings for some of the cases. Since then I've dumped all the .357 brass together. I do sort by manufacturer and use the Starline brass for bullseye competition, but no longer keep lots of .357 brass separate. (I checked: No change in accuracy.) Some of it must be in the high teens for reloadings by now.
And like Ol' Man River, it just keeps rollin' along. I've had 4 split necks and one case that split lengthwise down the body but only in the middle. That one may have been a range pickup. Anyhow, just recycle the brass that quits and keep on loading the rest.
I can't answer your questions 'cause I'm new to handloading.
I can testify to the feeling of that first box of .357 loads though. To me it was more satisfying than a new gun.
MY hand loads were going into tight little groups. WOW.
I loaded up 158 grain XTP's over five point five grains of Titegroup in Winchester .357 brass.
I shot them through my NEF Handi rifle. The group was so small I couldn't see it untill I walked up to the target. One inch at 50 yards! I was hooked for life.
Now I trust them enough to shoot them in my revolvers!
2400 is great for heavy bullets, but is sort of overkill for light bullets.
For light bullets like 125s power pistol and blue dot work great, and are cheaper than 2400 to load.
Ditto to what caz223 said. 2400 is my first choice for heavier bullets in 357 and 45 Colt. I use Blue Dot for the lighter bullets. Still, your loads should work very well for you.
I reserve the 2400 for the 158gr and heavier bullets and use Blue Dot for 125's. The best load I've found is 13.8grs of BD and just about any 125gr bullet. I've used Hornady, Sierra, and Remington (both the SJHP and the Golden Saber). This load sends them down range right around the factory advertised 1,450fps from my 4" barrel .357 handguns and over 1,500 from 6 inchers. Below is a picture I cut from a video taken of a friend of mine shooting this load from a Ruger 4-5/8" Black Hawk at an indoor range.
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