I'd suggest finding an identification table of British proof marks and checking to make sure that yours has the proper 'Nitro" proof stamps on it. Someone here may be able to help you with that, if you can post some photos. An approximate date of manufacture should be indentifiable from those, too.
Without examining it for condition personally it's not a good idea to make blanket assertions about the safety of any antique firearm of any make. When the possibility exists that the arm in question may not have been proofed for smokeless ("nitro") loads, it's downright dangerous.
Your safest course, IMO, is to have your revolver examined by a knowledgable professional and have them first confirm that it is sound enough to be fired before undertaking any actual use.
Should they approve its condition, and find that it was indeed proved with smokeless loads, then published loading data from current manuals should be okay in it.
As an added precaution given its age and unknown history I'd strongly suggest sticking to "starting" charges and using due caution when assembling any ammunition. A good way to get a "feel" for what safe loads should be like would be to buy a box or so of factory .455 ammunition from Fiocchi and try those first. It's fairly expensive, but it is the single source that i know of for new production ammo in this caliber. FWIMBW, the cases are excellent for reloading and should last quite a while with mild loads.
Hope this is of some help to you.