At 6'1" and 185 lbs. I am, perhaps, slightly larger than the average... but I find the STI Edge 2011 and Springfield GI Widebody 1911 fit my hand wonderfully.
The STI in .40 offers a considerable gain a capacity. The STI Edge is a superbly made, highly accurate, and reliable variant of the 1911.
Of course, I love standard 1911 configurations, but in my view, the capacity is less than I would like to have on hand if I found myself in a life and death defense situation. That's why despite my love of 1911's, Glocks are my primary choice for carry and home defense duty. Capacity can easily be the make or break factor when the chips are down. And reloads of lower capacity firearms, while a good thing, can't always come together quite as effectively as having higher capacity to begin with.
1911's were once my first choice for defense duty, but they no longer are. I love them, however.