I'll jump in, my experience is limited to all of one hour on the LNL AP and 101 rounds of .45 ACP as I just bought the thing today. I labored over which progressive to get and I don't have any regrets. Walked out of Cabelas with one sans case feeder for 470$ with 101 remington cases and 1lb of Hodgdon HP-38, went back and spent 32$ on a #1 shell plate and set it up.
Took very little time to set up. Cleaned out the powder measure and degreased it per instructions. I left all of the rest of the factory grease on the remaining parts. I had to adjust one of the timing paws to get it to time correctly. I loaded 101 pieces of .45 ACP using Lee dies and the Hornady powder measure and their primer system. Used CCI 300 LP primers and didn't have one issue priming. A little rough, but not any rougher than priming on my Lee Anniversary press. It went through all 101 cases without issue. All of my primers are below flush and straight on, no case damage, and consistent powder throws.
Well worth the cost for me. Now, granted, like I said, this is only 101 rounds, it's probably not even broken in, but it's working like a champ. I almost wish I had the case feeder too. Next time my budget allows I guess!