Depends on what it is.
My High Standard Victor and Trophy just get a once-over on the bolt and chamber face with a brush and a wipe down with a old piece of sweatshirt that has some oil on it. Very rarely do I break them down and run a brush through the bore.
Revolvers I usually run a brush through the chambers and barrel, follow up with a patch soaked in Hoppe's, then a patch with some gun oil, and then wipe them down. Since they don't get used as often as my Bullseye guns, I make sure they're not all gunky when they get put back in the gun safe.
My 1911's usually get cleaned just before a Bullseye match; field strip, clean out all the gunk, make sure the chamber is clean, the barrel reasonably so, re-lube the barrel, etc. per the diagram on the Bullseye forum, and then wipe them down.