Seems like I'm in the minority - although I am a 'computer guy' by trade since way back in the 70s (about 10 years before the PC was even invented), I do not use it for recording reload data.
My method is just a simple spiral binder in chronological order. Each loading session is listed by date first, then a number for each specific load done on that date (the date and sequence number is my "lot number"). I use about 10 lines for each load, with the load data on the left side of the page and resulting notes on performance, loading issues, etc. on the right side. No segregation by caliber. The current notebook lives on the reloading bench and gets thrown into the range bag when I head out with my targets and ammo. I still use an old manual Chrony from the early 90s, and those paper records get cross referenced with the lot number and thrown into a folder, rarely to ever be looked at again after the average speed and deviation is entered into the notebook.
Every batch of loaded ammo, box, case, bag or whatever, gets a label that included the lot number for that session, such as "7/12/15, #1" along with other basic info such as caliber, bullet type/weight and Chrony speed. If I ever want more info on the load, I just reference back to the lot number in the notebook.
I do keep another smaller notebook that is organized by caliber just to list my pet loads for quick reference, but the primary Log/Notebook works pretty much like a diary - when I suddenly get an idea that I should try a new load or different powder, bullet, etc., those thoughts just get written on the next available page. That way all of my reloading info and musings are in one place.
Over the years I have tried fancy pre-printed log sheets, log books and spreadsheets, but just cannot stick with them more than a day or two - the spiral notebook is just so much more simple and easy for me.