1. What measure are you using? RCBS Uniflow
2. What type of powder? W231, 2400, Reloder 7 (all "good-metering" powders)
3. Weight of your typical powder charge? W231: 3-5 gr 2400: 9-15 gr Re7: 29-31.5 gr
4. Are you consistently getting throws +/- 0.1 gr or better? Probably not. For handgun, I've decided there's no point trying to work up loads in 0.1 gr intervals because when it comes time to make them in "bulk" (using a single-stage press but without weighing each charge) they are going to vary as much as 0.1, so a 3.0 gr load might actually be 2.9 or 3.1 grains. Most of my handgun loads are light target loads so it doesn't really matter, since my shooting errors mask any accuracy errors resulting from a 0.1 gr difference in charges, and I'm not using max loads where an extra 0.1 gr is going to over-pressure the gun. For rifle and hunting handgun, my loads are max or close to max, so I weigh each charge (throw a light load on the Uniflow, then bring it up to spec with a trickler).
5. If worse than that, +/- how much? For handgun, I weight every 10 rounds or so, just because I'm paranoid, and they probably never vary more than about 0.1 gr with the powders I use.