I don't doubt that you can work up a load to achieve acceptable accuracy with the REAL bullet you mention. (I've heard they shoot pretty good). Sometimes a cast bullet requires a Wonder Wad over the powder for best results, sometimes not. However, I have found that some lead bullets, while tight when started at the muzzle are a bit looser once rammed past the first several inches of the bore, especially at the bottom of the barrel. Maybe because the rifling is deeper than the overall diameter of the bullet, and the lead is soft. This fact requires the hunter to be a little extra careful while transporting the gun in the woods and how one carries the rifle so as not to cause the bullet to become unseated. I can't say if this is a real issue of concern or just hypothetical. But I usually opt on the side of caution for hunting purposes. I don't mind shooting lead conicals on the range, but when I hunt, I often use the appropriate sabots with a medium .45 bullet, (260-300 gr. is available). I've found that sabots produce good first shot accuracy out of a cold, clean barrel. They just aren't as easy to load (require lub in the barrel) or as fun to play with on the range. So the choice is yours, you could cast .45's for sabots (knight's, etc..), or cast .50's for the ease of loading and range fun. (Most sabots really require a mallet to ram them home).