Can't speak for .45 but I have loaded 9mm with Magnum primers. Range loads so they were "mid-range". I don't see loading max loads to wear out my pistol just shooting targets.
I saw a good study done by one shooter who did a series of tests using different primers in the same firearm. He put a lot of work into it and had some nice charts and graphs. In the end there was more variations within a given load with same components that there was between "standard" and "magnum" primers.
As has been mentioned the only problem is when you get a really maxed out load as the magnum primers may cause a bit more pressure surge when the powder first lights off. They can change the pressure curve, as in raising max pressure, as you start accelerating the projectile. So, it gets complex as it relates to powder burn rates, how quickly the powder lights off, the weight of the projectile, etc.
Oh...you got my head spinning here....all I know is I have used Magnum primers, in a pinch, and had no issues. But....midrange loads, nothing "hot".