I would think whichever pistol you're the most proficient with should be your first inclination. I am a die hard 1911 fan and would love to recommend the
Commander, but given what's been said here and the fact that it could either be stolen or taken from you in a myriad of situations, I'd say go the middle ground and take what you're proficient with *and* could replace with little to no difficulty should the unthinkable occur.
I am also a Glock fan so I opted for the Glock 26 even though I'd love to say Commander. It's easy to use, very low maintenance (if you never get to lube it, it'll still run and no amount of humidity from the temperature variable room will cause rust), and loaded with good, quality ammunition, you have a fairly formidable defense package in your hands, simple as it may seem.
The only 'concealment' issue to consider is where to conceal it daily when you leave. I, too, agree that you should find a way to secure your lock box in your room. Unfortunately, there's only so much you can do, and so many places to hide it there.
A few years ago, I took two road trips to California during the summer and had the same decision you did. Back then, it was between a Sig P226, a Kimber Series I Stainless Compact, and a Glock 19 with two spare magazines. The Glock got the nod and I felt well armed with it during my travels. If I had to do it again, I'd probably opt for the same choice.
Let us know what you choose, and be safe down there.