I am only producing neck sized cartridges for my 30/06 and .458 Lott bolt action rifles these days -- full length re-sizing using the Lee hand press is much too strenuous for me, far beyond my present strength capabilities. Inasmuch as I use Hodgdon IMR Trail Boss powder (reduced loads) exclusively I haven't had to full-length re-size the 30/06 brass (result of low chamber pressure) even after +/- fifteen reloads. When that becomes necessary, I will do it using F/L dies in my dedicated reloading room.
And yes, always run your re-sized brass - and subsequently completed reloads - through your rifle (with the firing pin removed for safety) to check ease of chambering/bolt closure and proper feeding from the magazine. I always use the rifle I am reloading for as a gauge in this manner.
James