Both of your choices have excellent reputations for reliability but they have very different trigger mechanisms. The best trigger mechanism for a self-defense handgun can be and has been debated ad nauseam, but you will need to make a decision as to what is safest in your hands.
If you are not entirely clear on the different trigger mechanisms you might want to give this thread a read:
http://www.thehighroad.org/showthread.php?t=248556
Striker-fired trigger actions like those found on Glocks over the advantage of a consistent trigger pull with the same travel and weight for every shot. They also lack external safeties. Some people find the absence of a safety an advantage for a self-defense weapon because it eliminates the danger of forgetting to take it off in a crisis scenario. Others feel that an external safety reduces the chances of an accidental discharge. You have to decide for yourself.
A striker-fired action pistol typically has a much shorter and often somewhat lighter trigger pull than the DA (double action) trigger pull of a DA/SA pistol like the CZ P-07. This and the absence of an external safety demands absolute trigger finger discipline, i.e, you don't put your finger on the trigger unless you intend to fire. They also require extreme care in reholstering in that any foreign material that makes its way into the mouth of the holster can accidentally pull the trigger and cause an accidental discharge. This sounds easy, but there have been many negligent discharges caused by shooters putting their fingers in the trigger guard without meaning to and even without knowing that they did, and there have been more than a few NDs as a result of less than careful reholstering.
DA/SA autoloaders like the CZ will have a relatively long and heavier trigger pull for the first shot, unless you manually cock the hammer or do so by cycling the slide. The slide cocks the hammer with the first and every subsequent shot and those single action triggers pulls will be much shorter and lighter than the first. Some feel that the long and somewhat heavy DA trigger pull confers a safety advantage against a ND because it requires a more conscience effort to pull the trigger. But DA/SA autoloaders do require a shooter to master the transition from the DA trigger to the SA trigger which some find difficult.
The CZ P-07 is kind of nice because it offers an external safety if you want one. The pistol has a decocker/safety lever. As it comes stock, the lever functions as a decocker only, allowing you to safely drop the hammer if you wish to cease fire after either shooting the pistol or cocking the hammer. You can convert the decocker to a safety with a simple parts change.
So I think in your case the decision regarding the optimal manual of arms is going to be much more important than the particular gun manufacturer.