For precision ammo, yes. For plinking, general use, no.
Generally, it's best to trim pistol ammo (once-fired) the first time you load it, just to get a consistant case length. This is especially important with roll-crimped ammo like revolver loads. You want consistant case length so you have consistant seating depth and crimp.
The only real time you need to chamfer/deburr is after you trim, to get rid of the bit of metal that falls one way or the other. Most of the time, the case will be perfectly smooth after firing and not need a chamfer.
When you chamfer, be carefull to only remove the metal scraps, rather than case-wall material. If you end up with a razor sharp case mouth, you're chamfering too much. If yo udo this, your necks will split after only a few loads due to case hardening and working the necks. This is a step best done by hand, rather than machine. A variable speed drill can be used, but the important thing is to keep the rpm down to avoid removing too much material. Two revs is enough.