Not a gun gamer, but a 1911 carrier in the field for work. My safety comes off when I am aligned with the target at full extension and ready to shoot, immediately before my finger goes in the trigger guard. The safety goes on when I am in any position other than full extension, with the exception of one handed close contact shots indexing off my torso.
I also ride the safety, like JMorris illustrated. Much respect for Bill Wilson and Massad Ayoob, but the low thumb doesn't consistently work for me in terms of accuracy. A thumb riding the safety gets my scores marginally higher in qualifications and allows me to break the shots just a tad quicker, at least in my mind and experience. I've tried all three styles (the third being my left hand thumb flagpoling off my right hand thumb and the thumb over safety, left thumb parallel to the frame just works best for me. The drawback of the thumb on safety/parallel thumb is sometimes the friction can retard my slide and induce failure to feed/return to battery if they are too close/high, but that is a training issue. I'd rather have the more accurate shots.