I got to score a two times Bullseye National Champion at a local Bullseye Match. Turns out he is a multiple time PPC champion. I asked him the barrel life of his S&W 38 Special, he said he had about 600,000 rounds through it and it still shot 2"? groups at 50 yards. Most of his rounds were 148 LSWC 2.7 grains Bullseye. It was not a factory barrel, I have forgotten who made it, but that really does not matter in terms of barrel life. He did say, that in games where you had to make "major", it was not uncommon to have K frame forcing cones crack with 125 jacketed bullets.
I did ask what broke, and extractor stars and cylinder hands wore out on high mileage revolvers. Bud also had a hammer mounted firing pin break. Overall, unless you are shooting over pressure loads, doing something stupid like firing rocks down the barrel, or cleaning with steel wool, you are not going to shoot out a revolver barrel in this lifetime.