There is often some confusion over this:
Some Colt revolvers do lock up with no rotational movement when the trigger is held all of the way back. It would seem that this would be great, but only if the chamber (all six of them) are absolutely concentric with the bore. Otherwise lead will be shaved from one side of the bullet and likely spit out through the cylinder/barrel gap. To acomplish the ideal a lot a expensive hand fitting had to be done, by highly skilled and experienced final assemblers.
So it's easy to understand why Colt doesn't make guns like that anymore. If they did most buyers couldn't afford them.
Smith & Wesson, Ruger and Taurus (plus some others) let the cylinder wobble a little (the key word here is "little") so as it passes from the chamber into the barrel the bullet can align itself. The movement is so little that the above makers claim there is no loss of accuracy.
Freedom Arms still make revolvers where the chambers are locked concentric to the bore. They are very expensive, but well worth the money,