Well, I fall in this category. My choices and experiences:
Sig P-239 9MM with short trigger -- narrow grip, comfortable to shoot. My most oft carried handgun. The mag release and decocker are on the left side (no safety), but it's easy to use your middle finger to release mags, and your trigger finger to decock (keep your finger off the trigger...). Biggest drawback for me is the 8 round capacity mag.
Kel-Tec P-11 with mag finger extensions -- nice, narrow grip. Again, mag release on left side, but easy to use middle finger. Takes a lot of dry firing to get good with the DAO trigger pull. My second most common carry handgun. Ten round capacity mag.
Ruger KP95DC -- I know this one sounds out of place, but I can comfortably shoot the Ruger all day long. The grip just plain feels right. Ambi mag release, but I use my left middle finger so I'm consistent with my other handguns. No safety, ambidextrous decocker. Actually a fair carry gun with a Comp-Tac Gurkha holster.
Glock 23 3rd gen -- basically the same size as the Ruger, but has an uncomfortable grip due to the finger molding of the grip. Grip is fatter, too. I like the gun and can shoot it well, but it doesn't get carried very often.
Springfield Armory Mil-Spec 1911 45 ACP -- another surprisingly comfortable grip and trigger reach/pull. Very easy to shoot. Left side mag release, slide release, and safety. The standard safety is a bear for us lefties. Definitely an OWB with a good belt for me.
Ruger Super Blackhawk Bisley 7 1/2 " 44 Mag --
What a great gun to shoot! Comfortable grip. Best sight radius of all. Limited 6 round capacity. I carry it in a wheelbarrow.