Using those numbers, you get a mean powder weight of 24.48 grains with a standard deviation of 0.16 grains, and a mean bullet weight of 121.96 with a standard deviation of 4.25. Using the "68-95-99.7" rule (assuming a normal distribution) we can estimate that 95% of the powder weights will be between 23.99 and 24.97 grains and 95% of bullet weights will be between 117.7 and 126.2 grains. So, you can expect about 1 round per box to have a powder weight and/or bullet weight outside those ranges. Actually, the powder figure doesn't all that bad. The bullet weight range (about +/- 4%) figure may not even make of a difference to the average shooter if the weight is distributed evenly.