to kleanbore, that's my biggest fear also. one night after a trip to the E.R. i found myself and my wife at a cvs pharmacy at 0130. before we walked in, i loaded my glock 26 one in the chamber. now i know all glock owners will say, "that's how you should carry a glock"!. but for me i was just terrified. cmon guys, i know there's alot of us out there. my reason is, hey i'm not a cop,nor has had the extensive training to be carrying a glock with one in the chamber. i guess the thumb safety is more of a psychological thing for me. so same here, i will not carry a semi auto without a thumb safety. thanks kleanbore!