Doesn’t even have to be poor twist rate. A short action case isn’t going to push a 250grn bullet very fast. Even most standard bolt face long action cases won’t. A 300 grain bullet? Even slower. There’s no replacement for displacement.
Poor twist rate can be remedied by a custom barrel. Insufficient case capacity cannot be. This is why we hear guys say a 338-06 doesn’t “do anything” a .30-06 can’t do, or a 338wm doesn’t do anything a 300win mag can’t - but then we see a .338wm doing more than a .30-06, and a .375 H&H doing more than a .338wm. For most cartridges which aren’t terribly overbore, adding bullet diameter without adding bullet weight doesn’t add killing power, and typically, nor does adding bullet weight without adding case capacity. Maybe consider it this way - given a certain case capacity, say a .308win case, going down or up in bullet diameter too far into overbore or UNDERbore capacity ratios will limit your efficacy. In this example, a .243win, even in a fast twist barrel, isn’t really more than a whitetail rifle, whereas a .308win steps up a rung in game weight capability, however, the .358win really doesn’t. The .243win is overbore, the 308win less so, and the .358win relatively underbore.