If you have equivalent group size, MV within 50fps, both loads are in a velocity or accuracy node (depending upon before which alter you kneel), and SD’s under 10, I wouldn’t sweat a decision between either of those loads.
If I had loads that similar - both in the nodes, both low SD, both shooting small groups, aka statistically identical, then I might even run a test on my powder dispense system to see which charge weight it throws the most reliably - for example, I know one of my Chargemasters throws 41.8grn H4350 with only an error every 20 rounds or so, but 41.6 will overcharge 1 in 5-6, so loading takes considerably longer if I pick 41.6 than if I pick 41.8.
I’d also look at the neighbors. For example, I shot a velocity profile confirmation profile last week, 3 each of 8 progressive charge weights. Two nodes in the same place as my last two runs, but all 3 tests have shown the same larger divergence in SD above the high node than the error spread happening around my low node. Both nodes are wide with small error bars, but things wiggle a lot more if you inch outside of the high node than if you slip outside of the low. So I load the low.
Run your calculator - the difference in wind drift and drop even at 1,000yrds for ~45fps won’t change much for you, a couple tenths at most, and you’ll see absolutely no difference in vertical dispersion for a 2fps SD difference.
That all depends, if course, whether your “expanded” 10 round velocity profile included enough rounds of each to really establish statistically valid SD’s. If those are 3 shot SD’s, the weight I would give them is very different than if they are 10 shot SD’s.
