For defense there are some 125gr. magnum light loads.
Remington 125gr.Golden Saber.
Gold Dot Short Barrel .357 magnum would work as well.
WInchester 145 gr. Silvertip will stop people in their tracks and has a real world track record that is excellent. Actually, so does the Remington Golden Saber.
Corbon has this.
357 Mag 125gr DPX
[DPX357125-20]
The 140gr.-158gr. rounds seem to be the best for overall general use.
I do have to admit that I use Remington and Winchester +P .38 Special 158gr. LSWCHP for regular home and personal defense.
Gold Dot Speer 135gr.+P rounds come in second.
When I feel need for magnum power the Remington Golden Saber 125gr rounds, Hornady 140gr. rounds, Winchester 145gr. Silvertip, Or the Corbon 140gr. JHPs get the nod. It depends on the circumstances.
I do not live where large or go where large dangerous animals roam so the listed magnum rounds will get the job done for general purpose or for defense reasons. Even out in the field the wildlife wll go their way and leave humans alone.
If I felt the small black bear in this state were going to be a problem then the 158-180gr. rounds would be my pick. The bears here normally behave themselves.