From reading, the hippo goes away from ponds/rivers during the night to graze. Natives going to a river for water in the early morning wind up between hippo and home. Hard on natives.
Some writers claim that crocodiles in Africa and India kill more people than any other animal.
In North America, I'd venture that the Alaskan big bears would be top of the heap over anything else.
Africa? The lion is the top predator in terms of ability over such as a leopard. Odds are, from reading, it doesn't happen often enough to notice. But I'd bet nothing messes with a mature elephant...
In Asia, nothing matches the tiger.
Back in the 19th century, I've read, there were some caged situations with fights between lions and tigers. IIRC, it was a case of six of one, half-dozen of the other.
FWIW, Art