Here is my take.
Hey There ;
While I am by no means some highly paid video deer hunter, I have taken many.
I have hunted for more the 35 years now and for the last 20 have used .50 cal. Muzzleloaders. I am also an extreme accuracy nut. I do not use magnum loads. I now use the 250 or 300 grain Barns MZ all copper bullet. I want total expansion. Regardless if the round exits or not. Since I started using the 250 gr. at 1550 fps. I have not had an exit hole on a deer yet. The 300s do.
But. Even though I voted for the front shoulder, I normally shoot for the spine.
90% of my shots hit the spine and drop the deer in it's tracks. If I shoot lower and take a shoulder shot. The deer almost always will run atleast some.
I live and hunt in lower SW Michigan. We have many fences that are usually property lines. With over 750 to 800,000 deer hunters here, we must be very sure or loose a deer . Neighbors are nice till hunting lines are crossed.
We also many times hunt very close to those lines and must make sure that the deer does not take another step. If the deer were to run even 30 yards after being shot , we may not be able to go get it.
This may not be a big deal to some but is for many. The spine shot will drop deer in their tracks. We get the chance to do a lot of shooting . One farmer hates deer. He wants them all gone. He has now shut off his land to all but my son and I. We kill deer. We then , give the meat to those who need it.
There are some years we may shoot 6 to 8 deer each. All Very legal here.
The farmers have a lot of crop damage, and I now have seen this and know just how bad it can be.
The point is we get the chance to test , Bullets , guns , etc. We have learned what really works. Rifles are not an option here at all.
The farmer accross the street from him , has asked us to take coyotees off his land. They have become a problem.
We have even taken head shots , even at 100 yards. They just fall down. No bad meat there. We have taken new hunters at times. But most have a hard time killing deer. But then again most have killed their first deer with us and that makes us feel good about taking them.
Our rifles are Encores. They are very accurate and spine or head shots even at 100 yards are not hard to do if from a Bi-pod or other good rest.
Both rifle shoot around 1/2" at 100.
Just my 2 cents worth.