Bullseye.
Works in everything I own from 25ACP, through 9mm, 38 Special and 45 ACP.
My second choice for a go-to powder would be Hi-Skor 800-X since it works a little bit better in 9mm and that's the pistol cartridge I load the most, but still works well in the others.
But, I haven't always taken my own advice. I use Hi-Skor 700-X in 25 ACP since it can push 35 grain bullets to nearly 1,000 fps. I use HP-38 in 9mm since my Taurus likes it. 38 Special often gets Red Dot and my 185 grain 45 ACP loads get Blue Dot. Choosing a powder for each load allows me to tailor the performance of the load to my needs. But, if I could suddenly use only one powder, it would be Bullseye.
Works in everything I own from 25ACP, through 9mm, 38 Special and 45 ACP.
My second choice for a go-to powder would be Hi-Skor 800-X since it works a little bit better in 9mm and that's the pistol cartridge I load the most, but still works well in the others.
But, I haven't always taken my own advice. I use Hi-Skor 700-X in 25 ACP since it can push 35 grain bullets to nearly 1,000 fps. I use HP-38 in 9mm since my Taurus likes it. 38 Special often gets Red Dot and my 185 grain 45 ACP loads get Blue Dot. Choosing a powder for each load allows me to tailor the performance of the load to my needs. But, if I could suddenly use only one powder, it would be Bullseye.