Not that it will ever happen but....
I would like Colt to bring back the Anaconda in .41 Magnum, .44 Magnum, and .45 Colt. Of course I also want them to use all the same material call outs and production methods with modern improvements. Retain the same action as well, no need for the complexity of the Python lock work. So no MIM, all forged parts that are then machined to final dimensions. That is just to get started.
In addition to making the guns to the original standards (plus adding a caliber), I would like to see, and would be willing to pay for, a more refined action and more hand fitting. Make these revolvers nice.
While I'm also day dreaming Colt should offer a blued version as well with the best posible bluing they can turn out, and fancy walnut grios. Also for those of us who want a more subdued look or hard use revolver, the stainless guns should have the option of being salt bath nitrided. I'd also love to see chrome lined barrels and chambers.
The front sight should be easily exchanged for different styles and heights, with an assortment included with the revolver. Same for the rear sight blade. The top strap should be drilled and tapped for optics mounting, and Colt should develop and release mounts for popular optics the same time the revolver would be offered.
Barrel lengths of 3", 4", 5.25", 6.5", and 8".
The .45 Colt should also be offered with an accessory. 45ACP cylinder as an option.
As for which ones I'd buy if offered? First would be a 5.25" .44 Magnum, stainless steel with the salt bath nitride and chrome lined barrel and chambers. Then I would slowly acquire other examples as funds allowed.