I carried my CZ-45 (25acp - 2nd row 4th from the left) before the NAA guardian in .32 acp (directly below the CZ-45) came out (I couldn't afford a Seecamp). Like the OP said it is not optimal but it is still usable. Unfortunately size wise it is not the smallest kid on the block that it once was. As you can see my NAA guardian is physically smaller. The P32 directly above the CZ-45 is about the same dimensions but it is half the weight. For me weight is a bigger issue than physical size. Wearing shorts in the summer the P32 is barely noticeable, the CZ-45 is heavy and pulls my shorts down exposing my butt crack like a rapper... even with a decent belt. The NAA .22wmr mini-revolver to the right of the CZ-45 is considerably smaller and lighter... I will let you do your own ballistics comparison between .25acp and .22wmr. To the left of the CZ-45 is my DB9 which is my pocket carry of choice during the winter. The DB9 is considerably bigger and heavier than the CZ-45 but still pocket carriable in jeans for me with the advantage of shooting 9mm. Above the DB9 is my LCP which does not get much carry time any more being edged out by by the DB9 or P32 if I want smaller and lighter... but I still believe the LCP covers a very useful range in my pocket pistol line-up.
I can't ever foresee getting rid of the CZ-45 as it is worth more to me in fond memories and coolness than I could ever sell it for... BUT the days of the metal framed .25acp semi-autos have been far surpassed by todays plastic-fantastic guns!
I do find it interesting though that back in the day a pocket .25acp was a deadly weapon but since the advent of the internet and arm chair ballisticians any perp hit with a .25acp slug will merely wipe the .25acp slug off his leather jacket and laugh at you.