The way I see it is....if youre a handloader, the 10mm is probably your favorite semi auto cartridge due to versatility. I know it is mine....
It's a straight walled case and easy to load.
It can be loaded with light 155gr bullets to near as slow as 1000 fps for excellent target loads. The SWC cast bullets run great in my G20 and G40 with Lone/Alpha Wolf barrels and are very economical to shoot. It's an extremely accurate cartridge when loaded light and fired from the large framed, longer barreled gun like my G40 MOS
Spice things up and get a 180gr bullet over 1,400fps safely out of a handgun and without pushing pressure limits.
You can match the power factor and/or Muzzle energy loads, with the similar weight bullets of a heavy 9mm, 40S&W, 45ACP and 357 Magnum throughout the 10mm spectrum....
All with great accuracy and within just about any published load out there.
If I wasn't a handloader, I would be paying a lot of money for the Spicier hunting loads (what are they now a buck or 1.50 a shot), and downloaded target/plinking loads are basically non-existent on the factory market. The "regular" 10mm factory loads out there are running 180s about 1,200-1,250, which is no slouch, but I'd be seriously questioning whether I "needed" the cartridge for 45+p or hot 40 s&w performance (plus a narrow margin more)