I spent about 3 years, on and off, debating with myself whether or not to buy a 10mm. Maybe part of me was hopelessly waiting for S&W or Springfield to come out with a polymer 10mm to compete with Glock (I'm still waiting). Maybe part of me was trying to justify my 1911 as an all-around outdoor sidearm, if loaded with proper heavy flat nose +P loads. But every time I put the numbers to paper, the 10mm won hands down against all other common semi-auto cartridges, as well as some common revolver cartridges, when it comes to sectional density and energy, when using heavy hardcast loads from medium-length barrels. Not to mention the firepower of 15+1 rounds...
I finally broke down and bought a Glock 20SF about 2 months ago. I've got a year of black bear hunting, camping, and general "outdoors-ing" to do this year here in Oregon, and I'd like a capable, durable, lightweight sidearm to take along. Plus, the Glock is so ugly and durable, I don't care about getting it scratched up and dirty. Sure, I have a couple of .357 and .44 Magnum revolvers, but they are all heavier, wider, harder for me to shoot quickly and accurately, and hold MUCH less ammo than the Glock. 15 rounds of Double Tap 230-grain WFNGC @ 1,120 f/s. on my hip makes me feel a lot better than 6 rounds of any .357 Magnum.
The Glock SF models (which stands for short frame), feel just the slightest bit better in the hand than the regular models. In the G20SF, a few millimeters of width (from back strap to front strap) have been removed, allowing a slightly shorter trigger reach. I believe the Gen3 SF models have the same dimensions as their Gen4 counterparts, when used without any of the add-on back straps.
The Glock's polygonal barrel is not meant to be used with a large amount of lead bullets, but with quality hardcast gas-checked bullets (like the Double Tap referenced above), leading doesn't seem to be an issue with reviewers who have tested it. I've only put 10 or so rounds of this DT through my Glock so far, so I can't give you an accurate impression.
The only real downside I can think of with the Glock 10mm guns, is related to reloading (which is practically a necessity for 10mm). The pressure of the 10mm cartridge, coupled with Glock's rather loose tolerances in the chamber mouth area, give standard factory brass a little "belly" after being fired. I have successfully removed this small bulge from cases simply by running them through my RCBS sizing/de-capping die. But with multiple reloads of high-powered stuff, I'd keep a close eye on this symptom. I plan on using brand new brass for full-power reloads, and the once-fired brass for plinking loads. As others have mentioned, aftermarket barrels with much better chamber support can be found for the Glock 10mm guns, helping your brass last longer, and allowing you to shoot any kind of bullet you want.
The 10mm is a great round, with huge potential as an outdoor cartridge when loaded to it's top levels. And, as mentioned, 10mm ammo can often be found on gun store shelves when 9, 38, 40, 45, 357, and 44 are gone.