There is a noticeable difference between gel tests and real world shootings. Gel tests are important, and a great way to compare performance, but you need to always understand the penetration in gel and the penetration in a living body are not the same. Here is a great article that helps point that out.
https://www.activeresponsetraining.net/stop-worrying-about-overpenetration
https://www.activeresponsetraining.net/stop-worrying-about-overpenetration
Unfortunately the article is chock full of misinformation. For example:
Almost all of the rounds we tested penetrated a full 16″ of gelatin. Folks were asking me why a bullet would need to penetrate 16″ when the heart and other vital organs are only a few inches deep in the chest cavity.
The reason is that penetration in gelatin is not the same as penetration in human flesh and bone.
The human body is not a consistent medium. Muscle, fat, organ, and bone all have different mass, density, hardness, and flexibility. In general, a bullet will penetrate much deeper in gelatin that it will in human flesh.
Studies have shown that the the range of penetration in a human body, in any given shooting, can indeed be greater than the penetration in properly prepared and calibrated Type 250A ordnance gelatin, however the AVERAGE penetration depths are the same.
In addition soft tissue densities do not substantially affect penetration depth because at handgun bullet velocities the primary resistance to bullet penetration is inertial force as opposed to shear force.
Ordnance gelatin is currently the only realistic soft tissue simulant for terminal ballistics testing. Results in ordnance gelatin have been compared to thousands of actual shooting to verify and validate it's equivalence to living human soft tissues.
When bone is encountered a bullet's terminal performance cannot be accurately predicted due to several variables. Performance in bone is what it is. The only performance we want when bone is encountered is for the bullet to blast through to reach and destroy vital tissues, which are all soft tissues. To see how well bullets perform when bone is encountered, the FBI's windshield test provides a good indication. The RCMP performed a series of tests with rib bones and found them to have a negligible affect on a bullet's terminal performance.
When terminal performance in human tissues radically departs from terminal performance observed in properly prepared and calibrated Type 250A ordnance gelatin there's a good reason for it, one just has to look deeper to determine why. When the circumstances of these kinds of shootings are replicated using ordnance gelatin the results have been found to match.
The primary reason for the diminished penetration in an actual body is the presence of skin and bone.
Skin is very elastic. A bullet uses up a lot of energy stretching the skin before the skin actually breaks. Most ballistic experts believe that the skin itself is equal to one to two inches of gelatin penetration.
The resistance of skin to bullet penetration only matters when the bullet tries to exit the body. The bullet must stretch unshored skin enough to cause it to tear to allow the bullet to exit. Whereas an entrance wound on skin simply crushes skin tissue - there is no additional resistance caused by the skin stretching because the underlying body shores the skin.
We want a bullet that penetrates 12″-18″ of gelatin. That translates to roughly 6″-10″ of human flesh, depending on the structures hit.
This is false information that is easily disproved by studies comparing thousands of actual shootings to results observed in properly prepared and calibrated Type 250A ordnance gelatin.