I've got 4 Leupold's with the CDS:
3 VX6HDs: 1-6X, 2-12X42 and a 3-18X50
1 VX3HD: 2.5-8X36
I've only done the custom turret for one and that's the 1-6X that sits on my 3Gun AR. For that purpose it works great as that rifle only sees one load. A friend of mine has one on his .300WSM and he swears by it. He had a cap made for his 165 Nosler CT load and it's worked very well. We often do walk about shoots and I've watch him ring steel from 200-600 just from lasing the tgt and dialing in. Last fall he popped a nice Antelope at a little over 350yds by dialing a few clicks past the 300 mark.
I've left mine with the MOA turrets because I find it more flexible. I've got a couple different loads for each rifle depending on the game and conditions. All of mine have BDC reticles which are good out to 500 and I find the BDCs simpler and faster for hunting. My target and varmint rifles all wear MIL reticles, the X-Mas tree being my favorite.
For hunting I make little dope charts that I laminate and tape to the side of my stock for dialing in when I have time. All have the same data from 300 to 600yds in 50 yd increments for a 10MPH, 9 O'Clock wind. One of the columns is for the actual range the BDC indices are correct for. This way IF I travel I can make a new dope chart for the expected elevation, temp etc. for that area.
It's a nice capability to have, but honestly in close to 40+ years hunting big game in multiple states and several countries the vast majority of my shots have been under 300yds.