The Model 10 is a perfect 'starter' centerfire revolver. For home defense, you really don't need much more in it than 158 gr. semi-wadcutter hollowpoints. Easy to control and generally damaging to the recipient. Since it does not have adjustable sights, you learn how to do 'Kentucky Windage' and learn where different grain weights and loads shoot.
Don't really need +P in this, since if you want to start, you don't want to develop bad habits that a +P can scare you into. You want to learn holding and control and trigger control. If something is going to make a loud noise and whap your hand it's not conducive to learning how to shoot. However, .38 wadcutters, in the Model 10, will help you learn the right things to learn with a centerfire revolver.
That, plus they are almost indestructable and will pretty much always shoot so long as you take care of them.
I did know a cop who one day gave me his gun and asked if I could do something with it. Do something? I could not do anything. This guy would wear his gun in all weather in a regular drop strap holster. He never took it out to clean it after it was in snow, rain and cold. The bullets were green and the action was frozen shut from rust. I could hardly open the cylinder. If there had ever been a need to use it, he would never get off a shot. So bottom line, like any good tool, you need to take care of it.
Get the Model 10 and have some fun. When you want to graduate to a +P, just get a .357 magnum gun with a larger frame (L or N) or the Combat Magnum designation. (K-frame, but built for the .357)
Long winded answer here, but I hope it helps.
The Doc is out now.