For hunting in timber I like my 338-06, for more open country I like my 280 AI. If you look at the numbers the 338-06 normally has more energy out 200 yards or so and then starts dropping pretty fast. My 280 AI is far more pleasant to shoot and gives me 5 shots groups hovering around .75" at 200 yards over a bench. The 338-06 shoots under 1" at 100 yards but it's set up with a 3-9 scope with post reticle for closer shooting and it doesn't lend it's self to accuracy like the 280 AI with 4.5-14 Burris ballistic-plex does.
Accuracy will depend more on the reamer and gun smith than the cartridge itself.
Accuracy will depend more on the reamer and gun smith than the cartridge itself.