I know there is the feeling that heavier bullets are going to be somehow better. At close range, if the bullet does not expand, all that happens is a small through hole. A bud of mine, shooting 308 Win with 150 gr
Hornady SST bullets found that lung/rib cage shots allowed the deer to run off and die. There was not enough meat to make the SST bullet expand, and he would find the deer eaten by coyotes the next morning. However, when he aimed between the point of the shoulder and neck, there is a lot of bone and shoulder muscle in that location, the deer would fall, feet flay in the air, and die quickly. You have to adjust the construction of the bullet for the game, and impact point. Gut shots with 220 grain bullets are just as ineffective as 150 grain bullets.
Now this is a comment, out to 300 yards, I don't see why a 130 grain bullet would not be dynamite on deer. I did shoot one with a 130 gr in the 30-06, first bullet hit the hip/leg joint and totally broke the leg bone down to the knee, and hamburgered the leg meat. The next shot was through the neck and that ended the poor animals pain. A 30-06 will push a 130 faster than a 270 Win, and ole Jack OConnor made the 270 Win famous with 130 grain bullets. Stands to reason, a 130 in a 30-06 ought to give similar satisfaction.
A 150 grain expanding bullet will do everything you need in white tail. Get a good bullet, one that will reliably expand, and place it so it goes through the body cavity between the shoulders. Draw an imaginary line through the animal, to the shoulder point on the opposite side. There are lots of arteries, blood veins, lung tissue, and a heart in that area, and if you get any of those big ones, the animal will bleed out quickly.
Develop some loads, and verify for yourself that a 150 shoots well in your rifle.
don't go shooting at things 600 yards away unless you have a 600 yard zero, and a range finder. I got sighting shots.