Gosh where to begin. I have one of the first Browning A-bolt mountain hunters in 300 WSM. Well the first to come in here in Oshkosh.
Orcon's suggestion for AA-4350 is spot on. My 300 likes most of the medium burn rate powders, like the 4350's R-19 and H4831 SC. It does not do well with the slow stuff like 7828, H-870 or other slow magnum powders.
As for bullets, heavy for caliber is one way to keep from destroying a lot of meat, the other is a premium bonded or solid copper like Barnes, Nosler ELD-X or Hornady GMX. The Nosler accu-bond or Hornady interbond will work, but close up the still open too fast.
Back about 10 years I was hunting in some pretty dense woods, ammo was a 165 H-interbond. A small buck stepped out about 30 yards away, I didn't see the 1" poplar sapling in front of him Bullet center-hit that sapling, exploded on it, the only thing that hit that deer was lead fragments and possibly the empty jacket.
This years hunt was with the 165 H GMX with AA-4350, should go out at about 3000 FPS. 1+ groups @ 100, longest shot just over 100 yards. No shot presented itself, so called trophy management area meant darn few deer. Could only shoot one mature doe, and no buck other than horns outside the ears and well above the ears. Unfortunately deer that old are also smart, smarter than this old goat.