I'm shooting 225-grain Accubonds, and Re15 is THE powder for the Whelen, IMO---at least with the 225s and 250s. I'm getting almost 2700 fps and could get more if I wanted to push it, but the truth is it wouldn't matter in the practical sense and you really don't get that much increase in velocity per charge increase with this cartridge...I think that's one of the reasons it's so easy to keep velocities so consistent with the Whelen.