Hello again, win71!
Re: "accurate IMR 4350." Just to clarify, there is a powder called AA4350 by Accurate Arms (aka Western Powders) and a powder called IMR 4350 by IMR (aka Hodgdon). Hodgdon also has their Hodgdon H4350. Probably should not confuse these.
According to their websites, IMR does not list IMR 4350 for the .416 Rem., while AA lists AA4350 with 400 grain Hdy RN bullets as 78.3-87.0 grains, with velocites from 2155-2449 fps, and Hodgdon lists H4350 with the same bullet as 85.0-88.0 (C) grains; velocities 2305-2395 fps.