For my .44 Magnums (5 of them) I don't load anything faster than Unique, or lighter than 225 gr.bullets. On rare occations I'll load up some round balls over a load of W231. When I first began reloading the .44 in '86 there were a lot of magazine articles about reloading the magnum so I tried Bullseye under some lead bullets. Worked OK, but nothing special. I have no problem with loading small charges of fast powder in large cases, as my reloading style/methods are safe and I don't fear double charges. For me a .44 Magnum should shoot at least a 220 gr. bullet (and I have 200-300 429421 Lymans cast up and waiting) and be loaded to the velocity for the job (plinking 700-800 fps, hunting 1,000 or so fps) One of my pet loads is a 240 gr. LRNFP Ranch Dog over either a hefty but not max. load of Unique or 2400.