deer are not hard to kill with a handgun. Anchoring them is another story. What ever you use, be sure it is both intristically accurate, and that you can shoot it well. Accuracy is everything, and you are very wise to limit yourself to 65 yards. All the trouble I have had with deer being anchored with a handgun were not bullet performance, but were shooter failure to hit the vitals. A .38 wadcutter will kill a deer like hot lightning if you hit it through the heart, and believe it or not they will almost go all the way through on broadside shots through the lungs.
With that said, I like wide metplat flat points in my own handloads. Any of the reccomendations made above for Buffaloe bore, ets will work, but they are a might rowdy. I load a 310 grain flat point to about 1150 feet per second, and it will shoot all the way through them lengthwise. It makes a big bloody hole. A lighter bullet with just as big a metplat would probably do the same, but i would have to order an expensive custom mold. Hollowpoints sometimes work real well, and sometimes they don't. Hard cast wide metplat bullets always work, and you can get to the vitals from any angle with them. As above, though, you are a lot more important than the bullets. Shoot straight, and hit something the deer can't live without, and you will have a freezer full of meat.
