This should not be hard to understand.
The bullet will be very close to the chamber throat constriction in a dedicated ACP cylinder.
A .45 Colt bullet will be close to the chamber throat constriction in a .45 Colt cylinder.
The goal is to reduce as much uncontrolled bullet jump as possible, keeping the bullet in as straight a line as possible.
The distance between bullet nose and chamber throat will vary slightly, depending on bullet & COAL in both calibers, in dedicated cylinders.
If you just set a standard 230 ACP round base up next to an average 250-ish grain .45 Colt load, you can see there's much more difference in COAL between those two than you'll find in your average 158 grain .38 Special & 158 grain .357 COAL.
There's a lot more freebore bullet jump from a .45 ACP bullet in a chamber cut for .45 Colt.
This affects accuracy negatively in many ACP loads, when the ACP bullets have room to yaw & not strike the chamber throat constriction squarely.
This is not like the .38 in a .357 or a .44 Special in a .44 Magnum.
It's a phenomenon that does occur in this convertible Red.
As I said, I documented it in two different test sample guns, using the exact same ammo in both & under the same 25-yard testing protocols.
And, 6 or 8 years back, I tested a custom Super Red converted to fire .454, .45 Colt, and .45 ACP through the same modified cylinder.
Accuracy with the ACP was virtually worthless in that gun, and velocities were also lowered markedly, too.
It's real, it happens.
Shooting ACPs through the convertible Red simply causes a reduction in accuracy with many loads.
It's nowhere near as uniformly accurate as the convertible Blackhawk's ACP cylinder.
I happen to have one of those.
I'm not here, and I haven't anywhere else, been trying to tell anybody not to buy the convertible Red.
I just try to educate people talking about buying one intending to use it as primarily an ACP revolver.
It's a .45 Colt gun that also happens to take ACPs on the side, but not as well.
Denis