Conical or round ball? Your barrel will tell you. If it's a slow twist, say 1-66" or so, it'll likely only shoot round balls with any accuracy. T/C used a 1-48" twist in theirs, and they typically shoot both reasonably well. Your owner's manual should specify which type of projectile your rifle is suited for.
The owner's manual should also specify what the maximum powder charge recommended by the manufacturer is. Typically in anything larger than .45 FFg (or 2F) BP or substitute is used, although some guns perform better with FFFg (3F). I don't use substitutes, but as difficult as finding REAL black powder is becoming, I may have to start.
People who use BP substitutes tell me that Pyrodex is probably the worst one available as far as performance, fouling, and corrosion go. Hodgdon's Triple 7 (or 777) is supposed to be one of the better ones, from what I'm told.
I shoot 80 grains of 3F in my .54 flintlock for hunting, and 70 grains for plinking, with a patched round ball. I use the same loads in my .54 percussion. You'll likely have to try different patch thicknesses and ball diameters to see what your rifle prefers if you stick with patched round balls. Most anything will work for a patch lubricant, although some work better than others.