The answer to your question is, no.
Revolvers and high-pressure bottle-neck cartridges do no play well together.
When fired, the case slams back into the recoil shield on a revolver, and expands there.
Then, the expanded bottle-neck shoulder prevents the case from sliding back forward in the chamber to free the cylinder to turn.
That's why the straight wall 45-70, and other high intensity Magnum handgun rounds work so well, but little bitty bottle-neck ones like the old .22 S&W Jet didn't.
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