I'd prefer to use Swiss, Olde Eynsford, or Triple 7 as they produce more velocity for the same volume charge. Most of the velocities I've seen for Goex and Pyrodex, as well as the many other powders not mentioned, have given energy figures closer to a 38 Spl. But every now and then I see higher numbers closer to a 44 Spl. But I've seen people mention complete passthroughs of deer out at 100-125 yds with a PRB that only has 300 and something ft/lbs of energy or so. So it may well be good enough. I'd rather have more though, but my concern is more with hogs.