Well... let's look at the data you posted. Hodgdon gives a charge range of 5.1 to 5.6grn Universal, using the Hornady FP bullet at 1.200" First thing you are going to need to do is establish what your COL is going to be. Like Walk suggests, I would start at 1.260" because that's where I seat my 230grn RN bullets as well... it works good, and you are shooting those in a revolver anyway. Because I'm not familiar with Universal, I would start at 5.1grn and work up to 5.5grn as a tester, to make sure your pistol likes that powder and charge, and that it's safe.
QuickLoad tells me that the Rainier 230grn RN (plated) bullet, seated at 2.600", and 5.5grn Universal puts you perfectly in that 830fps range, at short of 19K PSI... that seems like a reasonable goal, and mimics what the Hodgdon data is saying. Assuming your ladder doesn't show issues, I would set your drop for 5.5grn, drop 10 and see what the average and the extremes are. You might need to set your drop at 5.4grn, and accept a few FPS loss for a further margin of safety. QuickLoad tells me you can go further with Universal and still be under max pressure for the .45ACP, but I am not recommending that, I'm saying that because if you set your drop up for 5.5grn, and you are within .2grn in either direction, you are still within the safety margin... according to QuickLoad. Universal is a mid-range powder, I would not expect it to get skwerrly and peak like a faster powder might do (think TiteGroup, WST, et al) that's one of the endearing features of a powder like Universal or Unique.
Your margin of safety can only be determined by you. I have been loading Unique for over 30 years... I know what it does, and what it doesn't do. I'm perfectly fine setting my drop for 6.4grn and going after 1000 rounds of .45ACP. Some handloaders can't handle powders that don't drop to the tenth every drop, if you are one of those, it would be my suggestion to find a different powder. If you want some load specifics... a particular COL or powder charge, etc... PM me and I'll run it through QuickLoad for you.