What target, what range, how many targets, etc
What do you intend to shoot at, at what range, and how much do you intend to shoot it? Can you tollerate gradually adjusting powder charges with a "trickler"? Are you going to experience considerable temperature changes?
My experience with bolt rifles is they like slower powders for heavier bullets. Heavier bullets give me a much larger feeling of recoil, so I don't like to shoot heavier bullets if I'm going to shoot a lot of them. For longer ranges, heavy bullets shed velocity slower, so at 600 yards a 168gr bullet from a .30-'06 is still supersonic, while a 150gr bullet (which started out faster) has become subsonic. When a bullet goes from supersonic to subsonic, groups usually increase tremendously. For some targets, you need a heavy bullet, such as large game, a heavy metal Silhouette target, and at long range.
If you intend something such as deer, I would suggest a 180gr bullet and work up to perhaps 56gr of IMR 4350. If you intend to shoot at something such as Metallic Silhouettes, I would suggest for the closer targets a lighter bullet such as a 150gr bullet and a powder such as 4895 or Varget, and 180's for the further ones.
If all you want to do is punch holes in targets at modest ranges such as 100 or 200 yards, a nice 125gr bullet would be fine, but I don't have any experience with those bullets in the -'06, so can't suggest a powder.
There are some loads where, if a rifle won't shoot well with it, it won't shoot well with anything. The above load with IMR 4350 and 180gr bullets is one of them.
Also, how much are you willing to fiddle around with your powder charges? Some powders such as the Ball/Spherical/globular powders meter beautifully and require little in the way of "trickling." Other powders such as the long extruded granule IMR powders meter poorly with all measures available today, and require a lot of trickling. In response, there are some Ball powders that mimic IMR powder speeds, as well as some "short cut" versions of IMR and other extruded "stick" powders.
Finally, higher ambient temperatures usually result in higher pressures, and the result is supposed to be more extreme with most Ball powders. It is supposed to be less noticeable with the stick powders.