Much of it may depend on what type of "neighbors" you want. I use the term neighbors loosely because you say you're looking for a large piece of property. OK, I'm going to be a huge snob for a second...The area others have been suggesting around Estacada, Oregon City, Clackamas, etc. can be beautiful, but these pockets are dangerously close to the sprawling East Portland slums like Gresham, Milwaukie, Troutdale, etc. No offense to anyone who lives out there, but that area makes the nightly news a lot more than areas across the river, if you know what I mean.
If I had lots of money (enough for a large piece of property in Northwest Oregon) I'd spend it west of the Willamette River, out toward wine country. This would include Sherwood, Tualatin, Newberg, and Dundee. These towns are just as close to Canby and Downtown as Estacada is, but are surrounded by a much more picturesque setting and a more "up-scale" clientele. You can still find property out there, plus you'd be very close to Tri-County Gun Club, an amazing facility. Good luck, and as others have said, try not to let on that you're from "the South".