The CZ-75 is an excellent sidearm, a wonderful reliable durable pistol renowned theworld over, with incredible ergonomics.
The CZ-100 was an attempt by CZUB to break into the polymer frame market, and build a police pistol to specifications provided. It has some interesting design points, like the one handed cocking mechanism on top of the slide, the recessed slide release, and the fact it is available outside the United States as the CZ-100 DAO and the CZ-110, DA/SA. The trigger mechanism is an interesting one, but resulted in a DAO pull that is, quite frankly, horrible. I have been told the CZ-110s trigger is actually pretty darn good, but the 110 is not imported right now.
I had a CZ-100 in 40, felt OK in the hand, well made, but the trigger meant I could not fire it accurately at any reasonable distance. Which was a darn shame. I sold it.