I agree with the need to put multiple rounds on target quickly. I also agree with shot placement. I also agree that you should have a gun on you, any caliber, and that's better than bare hands.
But seeing as how we're all advanced theorists here, I'll state my preferences. I shoot my 1911-style Colt .45 ACP faster and more accurately than the Glock 19 and Browning Hi Power I have owned. Re: shot placement, if the target stands still full frontal 7 yards away and isn't shooting back at the moment, I'll be happy to try for the "X" ring. If the target is moving, partially concealed, firing back, some distance away, and the light isn't quite right, I'll be happy with whatever blood I can draw, cover I can find, distance I can create, and exit I can find.
If it comes down to carrying a Kahr K9 all the time in a pocket instead of a .45 ACP Government Model just sometimes on the hip, by all means go 9mm. But for me, who is willing to wear the necessary covering garment, I will carry a .45 ACP or a .357 Magnum.
But as to the original thread topic... Oh, heck. Whatever floats your boat.